Energy-ranked selection — The lowest-energy conformer is selected as input for MACE-OFF
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This map illustrates the OsmAnd routing concept. The route starts in the Start Area Cluster (221558), moves to the nearest Border Point, and continues through precomputed Shortcuts across intermediate clusters. It then enters the Finish Area Cluster (221536) via another border point and finishes using local roads. This method speeds up routing by combining local search with efficient inter-cluster shortcuts.，这一点在谷歌浏览器下载中也有详细论述